Zebrafish as a Model for Studying Adult Effects of Challenges to the Embryonic Nervous System

Zebrafish is introduced as a model system to study environmental, chemical, and pharmaceutical challenges to the embryonic nervous system that can affect adult behavior/learning. The characteristics of the zebrafish system that make it possible to examine the developing nervous system in live embryos and larvae are presented. Gene discovery techniques, methodologies to generate fluorescent transgenic indicator embryos, as well as larval and adult zebrafish behavioral assays are described