Rituximab therapy for Severe and Persistent Lichenoid drug-reaction

We report on a patient with severe and fixed lichenoid drug-reaction.  She did not respond to 2 months treatment with high-dose corticosteroids.  Hence, Rituximab was given.  One month later, her lesions improved and remained stable for 14 months of follow up.    Keywords: fixed drug reaction, Prednesone, Rituximab