Standardization of an Ayurvedic Bhasma preparation and its evaluation as a potential haematinic agent

Background:Ayurveda arrangement of solution was very valued and worked on amid the brilliant time of Indian history. Three unique measurements of lauhabhasma were assessed for the haematinic movement and contrasted and that of Ferrous sulfate. The outcomes recommend that lauhabhasmas indicates noteworthy haematinic movement. Aim: The present study was designed as standardization of an Ayurvedic Bhasma preparation and its evaluation as a potential Haematinic Agent. Materials and Methods: It was evaluated by the terms of physiochemical parameters including colour, odour, taste, pH, total ash, acid insoluble ash, loss on drying, particle size determination, determination of floating property and determination of fineness and metallic luster in direct sunlight. For the pharmacological evaluations, rats were divided into 6 groups and administered as follows. Group 1: 1% Acacia; Group 2: 1% Acacia glue containing 1ml of supreme liquor for each 50 ml; Group 3: 1 ml of oral single dosage of 20mg/kg body weight/day ferrous sulfate; Group 4: I ml of oral single dosage of 10 mg/kg body weight/day of lauhabhasma; Group 5: 1 ml of oral single dosage of 15 mg/kg body weight/day of lauhabhasma and Group 6: 1 ml of oral single dosage of 20 mg/kg body weight/day of lauhabhasma. It was examined by different parameters such as RBCs, WBCs (Monocyte, Basophil, Eosinophil, lymphocytes) count, PCV, MCV, hemoglobin value, Mean Cell Hemoglobin Concentration (MCHbC) and Mean cell hemoglobin (MCHb).Results: In all the parameters, Ayurvedic preparation exhibited a potential hematinic effect. Conclusion:In conclusion, this examination may infer that the lauhabhasma might be exceptionally compelling ayurvedichaematinic operator and can be helpful in treatment of iron deficiency.Future aspect: In future, it might be a well-researched and promising source to subside anemia and various blood disorders. Keywords: Packed cell volume (PCV), Hemoglobin (Hb), Red blood cells (RBCs) and White blood cells (WBCs)