ENHANCEMENT OF ANTIBIOTICS IN BIOSYSTEM BY NIOSOMAL DRUG DELVERY METHOD

Therapeutics plays a vital role in this process for the treatment of diseases and the various ways of administering the drug in to the body. Niosome a vesicular drug carrier found its way in the field of pharmaceuticals. Bioavailability is attained when the drug is satisfied by all parameters which affect the activity of the drug like Adsorbtion, Distribution, Metabolism and Excretion. They are useful in carrying the drug to the target site, without any alteration in their composition and structure. The drug showed a very good activity on the microbial culture, there was also a good stability in the drug on pH. The drug was tested for all the parameters that affects the drug’s activity and then only used for delivering. In vitro drug release studies were carried out in order to study the drug’s release rate. The required quantity of the drug was delivered to the target site without any alteration of the drug (Ampicillin). Thus on the basis of studies conducted we can state that Niosomes possess great potential as drug delivery carriers orally. Keywords: Drug delivery, vesicles, therapy and noisome