DIABETIC EFFECTS OF POLYHERBAL FORMULATION OF LAWSONIA INERMIS AND AZADIRACHTA INDICA

The Present investigation was undertaken to evaluate the Polyherbal Formulation of Lawsonia inermis and Azadirachta indica in Alloxan & Streptozocin induced diabetic rats. In Alloxan induced diabetic studies samples were collected at 0, 2nd, 5th, 7th and 10th day after the rats had undervent the hyperglycaemic condition. The results showed that the Polyherbal formulation of Lawsonia inermis and Azadirachta indica (F1, F2, F3) found to be significant decrease (P<0.01) in blood glucose level as compared to the diabetic control group of animals while F4 & F5 were not significant (P>0.01) compared to the diabetic control group of animals. Streptozocin induced diabetic studies evaluates the Blood glucose level and the Diabetic body weight parameters over a period of fourteen days after treatment with Polyherbal Formulation of Lawsonia inermis and Azadirachta indica. On the day 21 the animals treated with Glimiperide drug (1mg/Kg), F1, F2, F3, F4, F5 were observed with significant increase in their body weight as compared to Diabetic control group of animals and also showed significant decrease (P<0.01) in Blood glucose level compared to the Diabetic control group. KEY WORDS: Diabetes, Lawsonia inermis, Azadirachta indica, Streptozocin, Alloxa