Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential
- Shah, Bhahwal Ali
- Chib, Renu
- Anand, Naveen
- Pandey, Anjali
- Kapoor, Kamini
- Bani, Sarang
- Gupta, Vivek K.
- K, Rajnikant
- Sethi, Vijay K.
- Taneja, Subhash Chandra
Publication date
January 2011
DOI Publisher
Elsevier BV ISSN
0960-894X Citation count (estimate)
5Abstract
Naturally occurring acetylated pseudoguaianolides and psilostachyin including their analogues were synthesized. The structure of semi-synthetic psilostachyin was also confirmed by X-ray crystallography. The anti-inflammatory potential of all the derivatives has been evaluated through in vitro expression of TNF-a, IL-1b and IL-6 in murine neutrophils
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