Abstract Introduction & Objective. Unintentional injuries from motor-vehicle crashes are the leading cause of death among children ages one to 19. On average, 4,500 children die every year from motor-vehicle crashes in the U.S., with total lifetime injury costs estimated at more than $40,000 and $240 billion in productivity losses. The majority of deaths and injuries are associated with improper use of restraint devices and alcohol, high speeds, and built environments that promote vehicle performance. The objective of this research is to evaluate the effects that primary prevention policies have had on reducing mortality from motor-vehicle crashes among children and adolescents in the U.S. Methodology. Retrospective study using panel data f...