"What we know is a drop; What we ignore is the ocean "Isaac NewtonThis time we open this edition of MATUA magazine with this one with this small but forceful phrase, from one of the greatest parents of all time, that reminds us that there is not much to find in this immense sea of knowledge that are the sciences This edition the magazine counts on authors of diverse countries like Venezuela, Ecuador and Colombia. Expert researchers in various branches of mathematics. Mathematical application, for example, Optimization of reference functions through optimization based on binary biogeography. Pure mathematics topics such as the construction of matrices of calculation of rank M, some inequalities of Hermite-Hadamard type for functions whose se...