Separation of Bisphenol Analogues by Capillary Electrophoresis

Bisphenol A (BPA) and its structural analogues (BPF, BPS, BPP, BPZ, BADGE, BPAP, BPAF) are used in the production of polycarbonate plastics for food and drink containers and epoxy resins to coat the inside of metal products. They have proven to have harmful endocrine disruptive effects in humans and in other life forms. Bisphenols released into the environment have profound impact on aquatic and terrestrial organisms and also pose a threat to fresh water ecosystems, thus necessitating their monitoring in the environment. A rapid and sensitive capillary electrophoresis method has been developed for the simultaneous determination of the eight closely-related bisphenol analogues. Factors affecting the analysis including micelle concentration, organic modifiers, type, pH, and concentration of background electrolyte were investigated in order to determine the optimum conditions for the separation of the eight bisphenol analogues. The potential of the proposed separation method was demonstrated by analyzing environmental waters which were fortified with the bisphenols