The comparison of proteins that are either up regulated or down regulated with respect to diabetic eye diseases revealed that more number of proteins exhibit variation with respect to diabetic eye diseases such as diabetic retinopathy and diabetic dry eye. We identified 396 proteins in the human tear fluid using top down MS analysis approach. Out of this we could identify 97 core tear protein which make core human tear proteome. The human tear proteome is composed of tear proteins like lactoferrin, poly Ig factor, serum albumin, Basic proline rich protein, lipocalin, lacritin, keratin, lysozyme, cystanin, serretoglobulin, heat shock proteins, glutathione-S- transferase and polyubiquitin to name the few. Additionally Aldehyde dehydrogenase, ...
Ocular dryness is a characteristic feature of primary Sjögren's syndrome (pSS). This may result in d...
Purpose. Lipocalins are an ubiquitous family of proteins binding lipophilic molecules, they may cont...
Tear is an accessible fluid for exploring biomarkers of dry eye disease. This study describes a fast...
Type 1 diabetes mellitus is a chronic illness resulting from β-cell destruction, usually leading to ...
Abstract Background Previous studies have shown a significant increase in tear protein peaks in the ...
Considering absence of invasiveness and side effects, tears emerge as a particularly attractive flui...
Tear film is a thin layer of non-newtonian fluid covering and protecting cornea and conjunctiva epit...
To understand the pathophysiology of dry eye disease (DED), it is necessary to characterize proteins...
Diabetic retinopathy (DR) is a sight threatening disorder which develops in nearly all patients with...
Diabetic retinopathy is the most common diabetic eye disease and a leading cause of blindness among...
We examined the tear film proteome of patients with Sjögren's syndrome (SS) and dry eye syndrome (gr...
In gist, there are several major findings emerging from the current study. First, several important ...
Ocular dryness is a characteristic feature of primary Sjögren’s syndrome (pSS). This may result in d...
We analyzed the tear film proteome of patients with dry eye (DE), meibomian gland dysfunction (MGD),...
Ocular dryness is a characteristic feature of primary Sjögren’s syndrome (pSS). This may result in d...
Ocular dryness is a characteristic feature of primary Sjögren's syndrome (pSS). This may result in d...
Purpose. Lipocalins are an ubiquitous family of proteins binding lipophilic molecules, they may cont...
Tear is an accessible fluid for exploring biomarkers of dry eye disease. This study describes a fast...
Type 1 diabetes mellitus is a chronic illness resulting from β-cell destruction, usually leading to ...
Abstract Background Previous studies have shown a significant increase in tear protein peaks in the ...
Considering absence of invasiveness and side effects, tears emerge as a particularly attractive flui...
Tear film is a thin layer of non-newtonian fluid covering and protecting cornea and conjunctiva epit...
To understand the pathophysiology of dry eye disease (DED), it is necessary to characterize proteins...
Diabetic retinopathy (DR) is a sight threatening disorder which develops in nearly all patients with...
Diabetic retinopathy is the most common diabetic eye disease and a leading cause of blindness among...
We examined the tear film proteome of patients with Sjögren's syndrome (SS) and dry eye syndrome (gr...
In gist, there are several major findings emerging from the current study. First, several important ...
Ocular dryness is a characteristic feature of primary Sjögren’s syndrome (pSS). This may result in d...
We analyzed the tear film proteome of patients with dry eye (DE), meibomian gland dysfunction (MGD),...
Ocular dryness is a characteristic feature of primary Sjögren’s syndrome (pSS). This may result in d...
Ocular dryness is a characteristic feature of primary Sjögren's syndrome (pSS). This may result in d...
Purpose. Lipocalins are an ubiquitous family of proteins binding lipophilic molecules, they may cont...
Tear is an accessible fluid for exploring biomarkers of dry eye disease. This study describes a fast...