The regulation of actin stress fibers (SF) are linked to the stability of microtubule (M1) structures. The exact method of interaction is not understood. To study the interaction, live cells containing fluorescent α-actinin were observed and treated with MT perturbing drugs as well as ATP-depletion. These treatments affect the stability of the microtubules and stress fibers respectively. A plasmid coding for fluorescent tubulin was also inserted into these cells to aid in observing both the MTs and SFs simultaneously. The observation relies on fluorescent microscopy and digital imaging. By observing the changes in the MTs and SFs in live cells, it is hoped that the mechanism of their interaction will be shown
AbstractActin stress fibers (SFs) play an important role in many cellular functions, including morph...
ABSTRACT Microtubules (MTs) are hollow cylindrical polymers composed of ab-tubulin heterodimers that...
The cytoskeleton of eukaryotic cells is primarily composed of networks of filamentous proteins, F-ac...
Interactions between microtubules and actin filaments (F-actin) are essential for eukaryotic cell mi...
International audienceThe crosstalk between the actin network and microtubules is essential for cell...
Despite considerable evidence that cytoplasmic microtubules play some role in guiding or controlling...
Cytoskeletal filaments provide cells with mechanical stability and organization. The main key player...
International audienceMicrotubules (MTs) are involved in many crucial processes such as cell morphog...
In recent years, research in cell biology has shown that mechanics is a key to cell response, differ...
Actin filaments assemble into diverse protrusive and contractile structures to provide force for a n...
One of the most exciting recent developments in cell biology is the recognition that the geometry, t...
Cytokinesis requires the proper interactions between microtubules and actin filaments (F-actin) at t...
<p>(<b>A</b>) β-tubulin, vimentin and phalloidin IF, β-actin mRNA, and PLA between β-actin mRNA and ...
Actomyosin stress fibers (SFs) play key roles in driving polarized motility and generating traction ...
To study the dynamics of stress fiber components in cultured fibroblasts, we expressed α-actinin and...
AbstractActin stress fibers (SFs) play an important role in many cellular functions, including morph...
ABSTRACT Microtubules (MTs) are hollow cylindrical polymers composed of ab-tubulin heterodimers that...
The cytoskeleton of eukaryotic cells is primarily composed of networks of filamentous proteins, F-ac...
Interactions between microtubules and actin filaments (F-actin) are essential for eukaryotic cell mi...
International audienceThe crosstalk between the actin network and microtubules is essential for cell...
Despite considerable evidence that cytoplasmic microtubules play some role in guiding or controlling...
Cytoskeletal filaments provide cells with mechanical stability and organization. The main key player...
International audienceMicrotubules (MTs) are involved in many crucial processes such as cell morphog...
In recent years, research in cell biology has shown that mechanics is a key to cell response, differ...
Actin filaments assemble into diverse protrusive and contractile structures to provide force for a n...
One of the most exciting recent developments in cell biology is the recognition that the geometry, t...
Cytokinesis requires the proper interactions between microtubules and actin filaments (F-actin) at t...
<p>(<b>A</b>) β-tubulin, vimentin and phalloidin IF, β-actin mRNA, and PLA between β-actin mRNA and ...
Actomyosin stress fibers (SFs) play key roles in driving polarized motility and generating traction ...
To study the dynamics of stress fiber components in cultured fibroblasts, we expressed α-actinin and...
AbstractActin stress fibers (SFs) play an important role in many cellular functions, including morph...
ABSTRACT Microtubules (MTs) are hollow cylindrical polymers composed of ab-tubulin heterodimers that...
The cytoskeleton of eukaryotic cells is primarily composed of networks of filamentous proteins, F-ac...
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