The human asset of the social brain is an evolved system that draws upon focal as well as globally connected brain mechanisms. These are dynamic and flexible anatomical routes operated for co−operation and co−ordination in intelligent behaviors. Divers cues and inputs from interaction, especially human social interaction are processed with reference to innate and acquired mental assets for inference and consequent generation of appropriate output (response). The focal and global connections are now subject to view with functional neuroimaging technology. Brain mapping approaches are now adding to the comprehensive understanding of neurophysiology. The technology-driven scientific advances have disclosed serious threat of environmental pollu...