DOIAbstract
The first choice of antihypertensive therapy should include an agent with the best metabolic profile, usually an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB), but additional agents should be used as needed to attain optimal blood pressure control, usually a diuretic or calcium-channel blocker (CCB) or both, whereas β-blockers should be used only if specially indicated for co-morbidities, such as in cases of coexisting coronary disease or chronic heart failure
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