A cyclic stretch and perfusion bioreactor was designed to culture large diameter engineered tissue tubes for heart valve applications. In this bioreactor, tubular tissues consisting of dermal fibroblasts in a sacrificial fibrin gel scaffold were placed over porated latex support sleeves and mounted in a custom bioreactor. Pulsatile flow of culture medium into the system resulted in cyclic stretching as well as ablumenal, lumenal, and transmural flow (perfusion). In this study, lumenal remodeling, composition, and mechanical strength and stiffness were compared for tissues cyclically stretched in this bioreactor on either the porated latex sleeves or solid latex sleeves, which did not permit lumenal or transmural flow. Tissues cyclically str...
It was previously demonstrated that combined flexure and flow in vitro conditioning augments enginee...
AbstractTissue engineering aims to repair and regenerate damaged tissues by developing biological su...
Tissue engineering strategies seek to regenerate cartilage tissue in vitro using a combination of ce...
In the past decades, vascular tissue engineering has made great strides towards bringing engineered ...
Objective: Three dimensional cell and tissue culture outcomes depend on mechanical forcesin their en...
The use of resorbable biomaterials to induce regeneration directly in the body is an attractive stra...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A pulsatile perfusion bioreactor system was designed and developed for the application of scaffold-b...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
The success of cardiovascular tissue engineering (TE) strategies largely depends on the mechanical e...
The ability to replicate physiological hemodynamic conditions during in vitro tissue development has...
The construction of tissue-engineered parts such as heart valves and arteries requires more than jus...
International audienceBACKGROUND: Perfusion bioreactors for tissue engineering hold great promises. ...
It was previously demonstrated that combined flexure and flow in vitro conditioning augments enginee...
AbstractTissue engineering aims to repair and regenerate damaged tissues by developing biological su...
Tissue engineering strategies seek to regenerate cartilage tissue in vitro using a combination of ce...
In the past decades, vascular tissue engineering has made great strides towards bringing engineered ...
Objective: Three dimensional cell and tissue culture outcomes depend on mechanical forcesin their en...
The use of resorbable biomaterials to induce regeneration directly in the body is an attractive stra...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
A pulsatile perfusion bioreactor system was designed and developed for the application of scaffold-b...
A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. ...
The success of cardiovascular tissue engineering (TE) strategies largely depends on the mechanical e...
The ability to replicate physiological hemodynamic conditions during in vitro tissue development has...
The construction of tissue-engineered parts such as heart valves and arteries requires more than jus...
International audienceBACKGROUND: Perfusion bioreactors for tissue engineering hold great promises. ...
It was previously demonstrated that combined flexure and flow in vitro conditioning augments enginee...
AbstractTissue engineering aims to repair and regenerate damaged tissues by developing biological su...
Tissue engineering strategies seek to regenerate cartilage tissue in vitro using a combination of ce...