Chronic periodontitis (CP) is a microbial dysbiotic disease linked to increased risk of oral squamous cell carcinomas (OSCCs). To address the underlying mechanisms, mouse and human cell infection models and human biopsy samples were employed. We show that the \u27keystone\u27 pathogen Porphyromonas gingivalis, disrupts immune surveillance by generating myeloid-derived dendritic suppressor cells (MDDSCs) from monocytes. MDDSCs inhibit CTLs and induce FOXP3 +
Long-lived monocytes, macrophages, and dendritic cells (DCs) are Toll-like receptor-expressing, anti...
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a wide range o...
Periodontitis is linked to polymicrobial interactions and the presence of Porphyromonas gingivalis. ...
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it...
A recent study demonstrated an association between the Porphyromonas gingivalis (Pg)infection and th...
Recent evidence has shown that P. gingivalis, a Gram-negative, anaerobic oral bacterium, is negative...
Many epidemiological and experimental studies have found a potential association between bacterial i...
BACKGROUND / AIMThe oral bacteria involved in the development of periodontitis alter the tissue cond...
Recent investigations revealed the relationship between chronic periodontitis, Porphyromonas gingiva...
Chemotherapy is not a first-line therapy for oral squamous cell carcinoma (OSCC), which is the most ...
Periodontitis is characterized by a chronic inflammation produced in response to a disease-associate...
Recent investigations revealed the relationship between chronic periodontitis, Porphyromonas gingiva...
There is increasing evidence for an association between periodontitis/tooth loss and oral, gastroint...
Porphyromonas gingivalis, an important periodontal pathogen, infects primary gingival epithelial cel...
p. 1-6Background: Apoptosis is a highly controlled process of cell death that can be induced by peri...
Long-lived monocytes, macrophages, and dendritic cells (DCs) are Toll-like receptor-expressing, anti...
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a wide range o...
Periodontitis is linked to polymicrobial interactions and the presence of Porphyromonas gingivalis. ...
Periodontitis is prevalent in half of the adult population and raises critical health concerns as it...
A recent study demonstrated an association between the Porphyromonas gingivalis (Pg)infection and th...
Recent evidence has shown that P. gingivalis, a Gram-negative, anaerobic oral bacterium, is negative...
Many epidemiological and experimental studies have found a potential association between bacterial i...
BACKGROUND / AIMThe oral bacteria involved in the development of periodontitis alter the tissue cond...
Recent investigations revealed the relationship between chronic periodontitis, Porphyromonas gingiva...
Chemotherapy is not a first-line therapy for oral squamous cell carcinoma (OSCC), which is the most ...
Periodontitis is characterized by a chronic inflammation produced in response to a disease-associate...
Recent investigations revealed the relationship between chronic periodontitis, Porphyromonas gingiva...
There is increasing evidence for an association between periodontitis/tooth loss and oral, gastroint...
Porphyromonas gingivalis, an important periodontal pathogen, infects primary gingival epithelial cel...
p. 1-6Background: Apoptosis is a highly controlled process of cell death that can be induced by peri...
Long-lived monocytes, macrophages, and dendritic cells (DCs) are Toll-like receptor-expressing, anti...
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a wide range o...
Periodontitis is linked to polymicrobial interactions and the presence of Porphyromonas gingivalis. ...