Two monoclonal antibodies (MC631 and MC813-70) raised against 4- to 8-cell stage mouse embryos and a human teratocarcinoma cell line, respectively, detect the stage-specific embryonic antigens, the previously defined SSEA-3 and SSEA-4, described herein. These antibodies were both reactive with a unique globo-series ganglioside with the structure shown below: (formula; see text) The antibodies were found to recognize sequential regions of this ganglioside, i.e., MC813-70 recognizes the terminal \u27a\u27 structure whereas antibody MC631 recognizes the internal \u27b\u27 structure. Thus, a set of two antibodies defines this unique embryonic antigen. During differentiation of human teratocarcinoma 2102Ep cells, the globo-series glyco...
Cell surface expression of stage specific embryonic antigen 1 (SSEA-1), or Lex (III3 FucnLC4), was i...
Two globoseries antigens (antigens borne on carbohydrate chains containing globoside), SSEA-3 and SS...
Stage-Specific Embryonic Antigen-1 (SSEA-1), originally discovered on mouse teratocarcinomas, has si...
Glycolipids in a cultured human teratocarcinoma cell line (2102Ep) were investigated. The major glyc...
A murine stage-specific embryonic antigen (SSEA3) is defined by reactivity with a monoclonal antibod...
A monoclonal antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immuni...
Monoclonal antibodies raised against and/or recognizing stage-specific antigens on preimplantation m...
A cloned human embryonal carcinoma (EC) cell line has been derived from a testicular teratocarcinoma...
Normal human tissues and various human tumors were surveyed by immunohistochemical techniques for ex...
A stage-specific embryonic antigen-2 (SSEA-2) found on murine preimplantation embryos is maximally e...
The glycan epitopes termed stage-specific embryonic antigens (SSEA) occur on glycoproteins and glyco...
AbstractThe use of cell surface antigens to characterise embryonic stem (ES) cells, and to monitor t...
Two neutral glycolipids carrying the stage specific embryonic antigen-1 (SSEA-1) and SSEA-3 determin...
C-9-1, a monoclonal IgM antibody raised against human null cell acute lymphocytic leukemia cells rea...
Molecules carrying SSEA-1 were isolated from [3H]galactose-labeled embryonal carcinoma cells by dete...
Cell surface expression of stage specific embryonic antigen 1 (SSEA-1), or Lex (III3 FucnLC4), was i...
Two globoseries antigens (antigens borne on carbohydrate chains containing globoside), SSEA-3 and SS...
Stage-Specific Embryonic Antigen-1 (SSEA-1), originally discovered on mouse teratocarcinomas, has si...
Glycolipids in a cultured human teratocarcinoma cell line (2102Ep) were investigated. The major glyc...
A murine stage-specific embryonic antigen (SSEA3) is defined by reactivity with a monoclonal antibod...
A monoclonal antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immuni...
Monoclonal antibodies raised against and/or recognizing stage-specific antigens on preimplantation m...
A cloned human embryonal carcinoma (EC) cell line has been derived from a testicular teratocarcinoma...
Normal human tissues and various human tumors were surveyed by immunohistochemical techniques for ex...
A stage-specific embryonic antigen-2 (SSEA-2) found on murine preimplantation embryos is maximally e...
The glycan epitopes termed stage-specific embryonic antigens (SSEA) occur on glycoproteins and glyco...
AbstractThe use of cell surface antigens to characterise embryonic stem (ES) cells, and to monitor t...
Two neutral glycolipids carrying the stage specific embryonic antigen-1 (SSEA-1) and SSEA-3 determin...
C-9-1, a monoclonal IgM antibody raised against human null cell acute lymphocytic leukemia cells rea...
Molecules carrying SSEA-1 were isolated from [3H]galactose-labeled embryonal carcinoma cells by dete...
Cell surface expression of stage specific embryonic antigen 1 (SSEA-1), or Lex (III3 FucnLC4), was i...
Two globoseries antigens (antigens borne on carbohydrate chains containing globoside), SSEA-3 and SS...
Stage-Specific Embryonic Antigen-1 (SSEA-1), originally discovered on mouse teratocarcinomas, has si...