Add to ORKGNearly 100 mouse mutations have been described as causing some type of abnormality of the skin or hair. As only a few of these mutations have been studied in detail, they remain an untapped resource for furthering knowledge of basic cutaneous physiology and understanding the pathophysiology of analogous diseases in humans. Several diverse murine mutations are discussed. These include asebia,: a mildly hyperkeratotoic disorder with sebaceous gland hypoplasia; ichthyosis,: an example of abnormal hair growth associated with hyperkeratosis; rhino: and hairless,: two related examples of congenital follicular malformations; and flaky skin:, a potential animal model of eruptive psoriasis
The skin and adnexa can be difficult to interpret because they change dramatically with the hair cyc...
An autosomal recessive genetic disease with clinical and histopathological skin features resembling ...
The recent advent of large scale reverse genetics and phenotyping projects has signalled a new era i...
Nearly 100 mouse mutations have been described as causing some type of abnormality of the skin or ha...
In this overview, we describe the advantages, disadvantages, and specific skin and hair abnormalitie...
In this overview, we describe the advantages, disadvantages, and specific skin and hair abnormalitie...
A comparison has been presented to illustrate many of the similarities in patterns of disease betwee...
Human hair disorders comprise a number of different types of alopecia, atrichia, hypotrichosis, dist...
The International Knockout Mouse Consortium was formed in 2007 to inactivate ("knockout") all protei...
A spontaneous, autosomal, recessive mouse mutation exhibiting mild scaly skin, progressive scarring ...
With the goal of increasing the number of genetic entry points for studying physiologic processes an...
Inbred laboratory mice are mammals and therefore are haired. Mice develop many of the same diseases ...
The International Knockout Mouse Consortium was formed in 2007 to inactivate (“knockout”) all protei...
With the goal of increasing the number of genetic entry points for studying physiologic processes an...
Laboratory mice have become the premier animal model for most human and domestic animal diseases, an...
The skin and adnexa can be difficult to interpret because they change dramatically with the hair cyc...
An autosomal recessive genetic disease with clinical and histopathological skin features resembling ...
The recent advent of large scale reverse genetics and phenotyping projects has signalled a new era i...
Nearly 100 mouse mutations have been described as causing some type of abnormality of the skin or ha...
In this overview, we describe the advantages, disadvantages, and specific skin and hair abnormalitie...
In this overview, we describe the advantages, disadvantages, and specific skin and hair abnormalitie...
A comparison has been presented to illustrate many of the similarities in patterns of disease betwee...
Human hair disorders comprise a number of different types of alopecia, atrichia, hypotrichosis, dist...
The International Knockout Mouse Consortium was formed in 2007 to inactivate ("knockout") all protei...
A spontaneous, autosomal, recessive mouse mutation exhibiting mild scaly skin, progressive scarring ...
With the goal of increasing the number of genetic entry points for studying physiologic processes an...
Inbred laboratory mice are mammals and therefore are haired. Mice develop many of the same diseases ...
The International Knockout Mouse Consortium was formed in 2007 to inactivate (“knockout”) all protei...
With the goal of increasing the number of genetic entry points for studying physiologic processes an...
Laboratory mice have become the premier animal model for most human and domestic animal diseases, an...
The skin and adnexa can be difficult to interpret because they change dramatically with the hair cyc...
An autosomal recessive genetic disease with clinical and histopathological skin features resembling ...
The recent advent of large scale reverse genetics and phenotyping projects has signalled a new era i...