Tests of physiological changes with age are illustrated by collagen denaturation times of tail tendon fibers, and urine concentrating abilities; the tests are evaluated using the following four criteria: change with age, repeatability, relationship to other assays, and relationship to longevity. These tests usually showed highly significant changes with age when mice of different ages were compared for nine mouse genotypes, however neither appeared to be related to subsequent longevities of individual mice. When average values for eleven mouse genotypes were compared, the mean longevities of the genotypes were not significantly correlated with their mean collagen denaturation times or mean renal concentrating abilities, testes at ...
Aging is associated with distinct phenotypical, physiological, and functional changes, leading to di...
We have quantified the frequency and proliferation of five subsets of primitive hematopoietic cells,...
Laboratory mice are predominantly used for one experiment only, i.e., new mice are ordered or bred f...
Tests of physiological changes with age are illustrated by collagen denaturation times of tail tendo...
Physiological and behavioral measurements were made in a cohort of 29-month-old male C57BL/6J mice t...
Ageing is a complex process characterised by a systemic and progressive deterioration of biological ...
Ageing is a complex process characterised by a systemic and progressive deterioration of biological ...
Aging is characterized generally by progressive and overall physiological decline of functions and i...
Mice of the C57BL/6J and CBA/HT6J inbred strains and their F1 hybrid were investigated at 67, 202, 4...
The relationship between chronological age (lifespan) and biological age (healthspan) varies amongst...
<p>(A) Concentrations of individual conjugated BAs in serum during aging and (B) proportions of them...
<p>(A) Concentrations of individual unconjugated BAs in serum during aging and (B) proportions of th...
International audienceAging is the major risk factor for the development of chronic diseases. After ...
New evidence refers to a high degree of heterogeneity in normal but also Alzheimer’s disease (AD) cl...
<p>(A) No differences were observed at ZT6 in the STR among young and old mice (t-tests, P>0.5 in al...
Aging is associated with distinct phenotypical, physiological, and functional changes, leading to di...
We have quantified the frequency and proliferation of five subsets of primitive hematopoietic cells,...
Laboratory mice are predominantly used for one experiment only, i.e., new mice are ordered or bred f...
Tests of physiological changes with age are illustrated by collagen denaturation times of tail tendo...
Physiological and behavioral measurements were made in a cohort of 29-month-old male C57BL/6J mice t...
Ageing is a complex process characterised by a systemic and progressive deterioration of biological ...
Ageing is a complex process characterised by a systemic and progressive deterioration of biological ...
Aging is characterized generally by progressive and overall physiological decline of functions and i...
Mice of the C57BL/6J and CBA/HT6J inbred strains and their F1 hybrid were investigated at 67, 202, 4...
The relationship between chronological age (lifespan) and biological age (healthspan) varies amongst...
<p>(A) Concentrations of individual conjugated BAs in serum during aging and (B) proportions of them...
<p>(A) Concentrations of individual unconjugated BAs in serum during aging and (B) proportions of th...
International audienceAging is the major risk factor for the development of chronic diseases. After ...
New evidence refers to a high degree of heterogeneity in normal but also Alzheimer’s disease (AD) cl...
<p>(A) No differences were observed at ZT6 in the STR among young and old mice (t-tests, P>0.5 in al...
Aging is associated with distinct phenotypical, physiological, and functional changes, leading to di...
We have quantified the frequency and proliferation of five subsets of primitive hematopoietic cells,...
Laboratory mice are predominantly used for one experiment only, i.e., new mice are ordered or bred f...