Clinico-electroencephalographic investigation on localization-related epilepsy in childhood

Clinico-electroencephalographic investigations were performed in 101 children with LRE and the results were as follows: 1） The patients with ILRE accounted for 50 cases, and S/CLRE for 51. The mean age at evaluation, and at onset and the mean observation periods were 13 years 1 month, 5 years 6 months and 7 years 2 months, respectively. 2） Four cases （10.3%） of 39 patients with BCECT showed seizures featuring a decreased level of consciousness. Rolandic discharges were seen to exist in the same proportion in right, left and bilateral brain regions. 3） Late-onset and early-onset idiopathic OLE was suspected in two （50%） and two of these four patients respectively. 4） We recognized two cases of ILRE which are not cited in the international classification; namely BPESG and BPEAS. There was a tendency towards seizure clustering in our BPESG patients. 5） Clinical analysis of 24 cases of TLE showed an etiology difference from TLE patients in the specialized epilepsy center. This result might reflect a hospital bias when dealing with epileptic syndrome. 6） During ictal events in 12 FLE children, there was a variety of characteristic features, such as gait automatisms, gestural automatisms and pelvic thrusting. 7） Characteristic seizure symptoms in 15 cases of OLE indicated visual symptoms in 2 cases, ocular deviation in 5 and abdominal autonomic symptoms such as nausea and vomiting in 5. 8） Ictal VEM revealed the seizure semiology of infants, which are usually difficult to analyze. This method demonstrated definite localization of onset of EEG activity signifying that GTCs seen in our patients were PS with SGS originating from certain area.departmental bulletin pape