Add to ORKGRestriction endonuclease analysis of genomic DNA was carried out for three types of dwarf mice (Little, Ames dwarf and Snell dwarf) that have genetic defects in GH expression. We found the GH genes to be present in homozygotes for each mutant allele as well as in their control litter-mates. These three type of dwarf mice may be useful in studying the molecular basis of inherited GH deficiency and as models for analogous genetic disorders of human GH expression
The growth hormone-releasing hormone receptor (GHRHR) is a member of the family of G protein-coupled...
Although most cases of short stature associated with growth hormone (GH) deficiency are sporadic and...
Two knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated inde...
Analysis of GH gene structure in the mouse permits evolutionary comparisons with GH gene structure i...
There are three recessive genes (little, Snell, and Ames) which cause dwarfism and GH deficiency in ...
A new autosomal recessive mutation in the mouse, little (lit), has been shown to be located on Chrom...
The SMA1-mouse is a novel ethyl-nitroso-urea (ENU)-induced mouse mutant that carries an a-->g mis...
国立情報学研究所で電子化したコンテンツを使用している。We identified several mutations in the intron 3 of human growth hormone g...
A DNA fragment size variant for the growth hormone gene, Gh, has been identified among inbred strain...
The new mouse mutation little (lit) in the homozygous state causes a pituitary deficiency involving ...
The Ames dwarf is a mouse mutant characterized by a reduced body size and infertility caused by lack...
Ames dwarf (df) is an autosomal recessive mutation characterized by severe dwarfism and infertility....
Nuclear DNA from individuals belonging to nine different families in which two sibs were affected wi...
Smallie (slie), a spontaneous, autosomal-recessive mutation causes dwarfing and infertility in mice....
Nuclear DNA from four individuals with familial isolated growth hormone (somatotropin) deficiency (I...
The growth hormone-releasing hormone receptor (GHRHR) is a member of the family of G protein-coupled...
Although most cases of short stature associated with growth hormone (GH) deficiency are sporadic and...
Two knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated inde...
Analysis of GH gene structure in the mouse permits evolutionary comparisons with GH gene structure i...
There are three recessive genes (little, Snell, and Ames) which cause dwarfism and GH deficiency in ...
A new autosomal recessive mutation in the mouse, little (lit), has been shown to be located on Chrom...
The SMA1-mouse is a novel ethyl-nitroso-urea (ENU)-induced mouse mutant that carries an a-->g mis...
国立情報学研究所で電子化したコンテンツを使用している。We identified several mutations in the intron 3 of human growth hormone g...
A DNA fragment size variant for the growth hormone gene, Gh, has been identified among inbred strain...
The new mouse mutation little (lit) in the homozygous state causes a pituitary deficiency involving ...
The Ames dwarf is a mouse mutant characterized by a reduced body size and infertility caused by lack...
Ames dwarf (df) is an autosomal recessive mutation characterized by severe dwarfism and infertility....
Nuclear DNA from individuals belonging to nine different families in which two sibs were affected wi...
Smallie (slie), a spontaneous, autosomal-recessive mutation causes dwarfing and infertility in mice....
Nuclear DNA from four individuals with familial isolated growth hormone (somatotropin) deficiency (I...
The growth hormone-releasing hormone receptor (GHRHR) is a member of the family of G protein-coupled...
Although most cases of short stature associated with growth hormone (GH) deficiency are sporadic and...
Two knockout mouse models for the autism candidate gene Neurobeachin (Nbea) have been generated inde...