This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5\u27 and 3\u27 boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalia...
Regulated transcription controls the diversity, developmental pathways and spatial organization of t...
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the prem...
We report the construction of the mouse full-length cDNA encyclopedia,the most extensive view of a c...
This study describes comprehensive polling of transcription start and termination sites and analysis...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. Th...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. Th...
Mice have been a long-standing model for human biology and disease. Here we characterize, by RNA seq...
Regulated transcription controls the diversity, developmental pathways and spatial organization of t...
Regulated transcription controls the diversity, developmental pathways and spatial organization of t...
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the prem...
We report the construction of the mouse full-length cDNA encyclopedia,the most extensive view of a c...
This study describes comprehensive polling of transcription start and termination sites and analysis...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. Th...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. Th...
Mice have been a long-standing model for human biology and disease. Here we characterize, by RNA seq...
Regulated transcription controls the diversity, developmental pathways and spatial organization of t...
Regulated transcription controls the diversity, developmental pathways and spatial organization of t...
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the prem...
We report the construction of the mouse full-length cDNA encyclopedia,the most extensive view of a c...