REVITALISASI OBAT GENERIK: HASIL UJI DISOLUSI OBAT GENERIK TIDAK KALAH DENGAN OBAT BERMEREK

The government through the Ministry of Health is very serious about revitalizing the use of generic medicines by issuing a policy that stipulated in the Regulation of the Minister of Health No. HK. 02.02/Menkes/068/1/2010 about duty to use generic medicines in government health care facilities. To maximize the use of generic medicines, it is very important to improve the understanding and trust of society that the quality, safety and effectiveness of generic medicines are similar to branded medicines. In addition, if there many researchs and the studies of generic medicines, they would increase the knowledge of health professionals, especially doctors, they may not hesitate to prescribe generic medicines. Since the quality as a basis of reference to establish the truth of the eficacy and safety, while the availability of certain products can be demonstrated in vitro. Studies of medicines dissolution, can give the same indication with medicines bioavailability. Ideally, in vitro medicines dissolution correlates bioavailability in vivo. The researchs results of dissolution test generic medicines of Amoxiciline 500 mg tablets, Isosorbit Dinitrat 5 mg tablets and Omeprazole capsules show that generic medicines have a better dissolution test results when compared to branded medicines. Keywords : revitalizing, generic drugs, dissolution tes