Introduction. Free trisomy 21 is responsible for 95% of Down syndrome cases. Advanced maternal age and susceptible recombination patterns are recognized risk factors associated to Down syndrome. Maternal origin of trisomy occurs in approximately 90% of cases; paternal and mitotic origin share the remaining 10%. However, the recombination events that serve as a risk factors for trisomy 21 have not been carefully characterized. Objective. To analyze and validate observations in a sample of Colombian trysonomy 21 cases.Materials and methods. Twenty-two Colombian families were selected, each with one affected Down syndrome (free trisomy 21) child. Microsatellite polymorphisms were used as DNA markers to determine the parental/stage origin of no...
CONTEXT AND OBJECTIVE: Polymorphisms in genes involved in folate metabolism may modulate the materna...
El aborto recurrente se presenta entre el 1 y 7% de las parejas. Su etiología comprende factores gen...
El síndrome Down (SD) es la trisomía más común en humanos, presentándose en 1 de cada 745 nacidos vi...
Introduction. Free trisomy 21 is responsible for 95% of Down syndrome cases. Advanced maternal age a...
Down Syndrome (DS) is a chromosomal aberration where 21 chromosome is total or partial duplicate. DS...
La no segregación es el fracaso de los cromosomas homólogos en separarse correctamente durante la me...
Introduction: Down syndrome is the most common human chromosomopathy and the main cause of congenita...
Objetivo: evaluar la presencia del polimorfismo C677T del gen de la enzima MTHFR como posible factor...
Introduction. Gene APOEε4 allele polymorphisms have been examined in Down syndrome because of the re...
Down syndrome (DS) is a complex genetic and metabolic disorder attributed to the presence of three c...
Introduction: Previous reports have identified a region of chromosome 21 known as Down ayndrome crit...
A result with chromosomal alteration was analyzed from a database consisting of a total of 4755 samp...
Prevalence of Down syndrome in the CEHANI-ESE in San Juan de Pasto Colombia. 1998-2003 Background: T...
Los laboratorios de genética forense, analizan actualmente polimorfismos de ADN del tipo Microsatéli...
Amniotic fluid was collected from 31 high risk pregnancy women in order to conduct prenatal diagnosi...
CONTEXT AND OBJECTIVE: Polymorphisms in genes involved in folate metabolism may modulate the materna...
El aborto recurrente se presenta entre el 1 y 7% de las parejas. Su etiología comprende factores gen...
El síndrome Down (SD) es la trisomía más común en humanos, presentándose en 1 de cada 745 nacidos vi...
Introduction. Free trisomy 21 is responsible for 95% of Down syndrome cases. Advanced maternal age a...
Down Syndrome (DS) is a chromosomal aberration where 21 chromosome is total or partial duplicate. DS...
La no segregación es el fracaso de los cromosomas homólogos en separarse correctamente durante la me...
Introduction: Down syndrome is the most common human chromosomopathy and the main cause of congenita...
Objetivo: evaluar la presencia del polimorfismo C677T del gen de la enzima MTHFR como posible factor...
Introduction. Gene APOEε4 allele polymorphisms have been examined in Down syndrome because of the re...
Down syndrome (DS) is a complex genetic and metabolic disorder attributed to the presence of three c...
Introduction: Previous reports have identified a region of chromosome 21 known as Down ayndrome crit...
A result with chromosomal alteration was analyzed from a database consisting of a total of 4755 samp...
Prevalence of Down syndrome in the CEHANI-ESE in San Juan de Pasto Colombia. 1998-2003 Background: T...
Los laboratorios de genética forense, analizan actualmente polimorfismos de ADN del tipo Microsatéli...
Amniotic fluid was collected from 31 high risk pregnancy women in order to conduct prenatal diagnosi...
CONTEXT AND OBJECTIVE: Polymorphisms in genes involved in folate metabolism may modulate the materna...
El aborto recurrente se presenta entre el 1 y 7% de las parejas. Su etiología comprende factores gen...
El síndrome Down (SD) es la trisomía más común en humanos, presentándose en 1 de cada 745 nacidos vi...