A specific prediction equation is necessary to estimate peak oxygen uptake in obese patients with metabolic syndrome

International audiencePurposeThe aims were to: (1) compare peak oxygen uptake (V˙O2peak) predicted from four standard equations to actual V˙O2peak measured from a cardiopulmonary exercise test (CPET) in obese patients with metabolic syndrome (MetS), and (2) develop a new equation to accurately estimate V˙O2peak in obese women with MetS.MethodsSeventy-five obese patients with MetS performed a CPET. Anthropometric data were also collected for each participant. V˙O2peak was predicted from four prediction equations (from Riddle et al., Hansen et al., Wasserman et al. or Gläser et al.) and then compared with the actual V˙O2peak measured during the CPET. The accuracy of the predictions was determined with the Bland–Altman method. When accuracy was low, a new prediction equation including anthropometric variables was proposed.ResultsV˙O2peak predicted from the equation of Wasserman et al. was not significantly different from actual V˙O2peak in women. Moreover, a significant correlation was found between the predicted and actual values (p < 0.001, r = 0.69). In men, no significant difference was noted between actual V˙O2peak and V˙O2peak predicted from the prediction equation of Gläser et al., and these two values were also correlated (p = 0.03, r = 0.44). However, the LoA95% was wide, whatever the prediction equation or gender. Regression analysis suggested a new prediction equation derived from age and height for obese women with MetS.ConclusionsThe methods of Wasserman et al. and Gläser et al. are valid to predict V˙O2peak in obese women and men with MetS, respectively. However, the accuracy of the predictions was low for both methods. Consequently, a new prediction equation including age and height was developed for obese women with MetS. However, new prediction equation remains to develop in obese men with MetS