The design of DNA directed nitrogen mustards has led to the development of compounds with increased specificity for DNA and enhanced cytotoxicity compared to similar untargeted mustards. By linking an intercalating anthraquinone chromophore to a nitrogen mustard function it was anticipated that such compounds would also have the potential to irreversibly inhibit the topoisomerase II (topo II) enzyme
We describe several new aromatic nitrogen mustards with various aromatic substituents and boronic es...
A series of bisnaphthalimide derivatives were synthesized and evaluated for growth-inhibitory proper...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
1-{2-[N,N-bis(2-chloroethyl)amino]ethylamino} -4- {2-[N,N-(dimethyl)amino]ethylamino} - 5.8-dihydrox...
Alchemix is an exemplar of a class of anthraquinone with efficacy against multidrug resistant tumors...
Cancer is a term used for diseases characterized by out of control cell-growth and rapid creation of...
NoA novel series of 1,4-disubstituted chloroethylaminoanthraquinones, containing alkylating chloroet...
NoChloroethylaminoanthraquinones are described with intercalating and alkylating capacity that poten...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are req...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
A novel series of 1,4-disubstituted chloroethylaminoanthraquinones, containing alkylating chloroethy...
Cancer has long been known as a dreadful disease characterized by uncontrolled proliferation of tumo...
NoA novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-...
We describe several new aromatic nitrogen mustards with various aromatic substituents and boronic es...
A series of bisnaphthalimide derivatives were synthesized and evaluated for growth-inhibitory proper...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
1-{2-[N,N-bis(2-chloroethyl)amino]ethylamino} -4- {2-[N,N-(dimethyl)amino]ethylamino} - 5.8-dihydrox...
Alchemix is an exemplar of a class of anthraquinone with efficacy against multidrug resistant tumors...
Cancer is a term used for diseases characterized by out of control cell-growth and rapid creation of...
NoA novel series of 1,4-disubstituted chloroethylaminoanthraquinones, containing alkylating chloroet...
NoChloroethylaminoanthraquinones are described with intercalating and alkylating capacity that poten...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are req...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
A novel series of 1,4-disubstituted chloroethylaminoanthraquinones, containing alkylating chloroethy...
Cancer has long been known as a dreadful disease characterized by uncontrolled proliferation of tumo...
NoA novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-...
We describe several new aromatic nitrogen mustards with various aromatic substituents and boronic es...
A series of bisnaphthalimide derivatives were synthesized and evaluated for growth-inhibitory proper...
A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-di...
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