The main challenge in tendon injury management is suboptimal tissue healing that fails to re-establish original tendon function. Tissue bioengineering is a promising approach for tendon therapy, with potential to improve its functional outcomes. However, evaluation criteria for tissue-engineered tendon are unclear due to the lack of specific markers of differentiated tendon. The study aim was to identify a panel of genes that characterised tendons in comparison to cartilage or muscles and validate those genes, both in human and key species used as models for tendon diseases. Gene expression profiling of rat tendon and cartilage in whole-tissue samples and primary tenocytes and chondrocytes was undertaken using two independent microarray pla...
Tendon injury can occur from activity-induced overuse, complete laceration or aging-related degenera...
Tendons are dense connective tissues with a hierarchical polarized structure that respond to and ada...
Tendon healing is complex to manage because of the limited regeneration capacity of tendon tissue; s...
Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation, leading...
Tendons are fibrous connective tissues that connect skeletal muscle to bone. Functioning primarily t...
Background Tendons are dense connective tissues subjected periodically to mechanical stress upon wh...
International audienceTendon is a crucial component of the musculoskeletal system. Tendons connect m...
Abstract Background Prolonged inflammation during tendon healing and poor intrinsic healing capacity...
Current treatments for tendon injuries often fail to fully restore joint biomechanics leading to the...
Each year, 30 million musculoskeletal disorders are reported in the UK. It is estimated that more th...
Background: Multipotent mesenchymal stromal cells (MSC) can be recovered from a variety of tissues i...
Tendinitis is a common cause of breakdown injury in equine athletes and accounts for 30% to 50% of a...
Tendon cells exist in a dense extracellular matrix and mechanical loading is important for the stren...
Tendon and ligament injuries present a significant socioeconomic problem. Tissue engineering has bec...
Tendon injury is painful and often debilitating, and is a one of the most prevalent soft tissue inju...
Tendon injury can occur from activity-induced overuse, complete laceration or aging-related degenera...
Tendons are dense connective tissues with a hierarchical polarized structure that respond to and ada...
Tendon healing is complex to manage because of the limited regeneration capacity of tendon tissue; s...
Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation, leading...
Tendons are fibrous connective tissues that connect skeletal muscle to bone. Functioning primarily t...
Background Tendons are dense connective tissues subjected periodically to mechanical stress upon wh...
International audienceTendon is a crucial component of the musculoskeletal system. Tendons connect m...
Abstract Background Prolonged inflammation during tendon healing and poor intrinsic healing capacity...
Current treatments for tendon injuries often fail to fully restore joint biomechanics leading to the...
Each year, 30 million musculoskeletal disorders are reported in the UK. It is estimated that more th...
Background: Multipotent mesenchymal stromal cells (MSC) can be recovered from a variety of tissues i...
Tendinitis is a common cause of breakdown injury in equine athletes and accounts for 30% to 50% of a...
Tendon cells exist in a dense extracellular matrix and mechanical loading is important for the stren...
Tendon and ligament injuries present a significant socioeconomic problem. Tissue engineering has bec...
Tendon injury is painful and often debilitating, and is a one of the most prevalent soft tissue inju...
Tendon injury can occur from activity-induced overuse, complete laceration or aging-related degenera...
Tendons are dense connective tissues with a hierarchical polarized structure that respond to and ada...
Tendon healing is complex to manage because of the limited regeneration capacity of tendon tissue; s...