Aqueous Humor Dynamics in Uveitic Eyes

PURPOSE: To investigate aqueous humor dynamics in uveitic eyes DESIGN: A cross-sectional study PARTICIPANTS: Patients with recurrent(≥3 attacks) anterior uveitis(now quiescent) and being treated for glaucoma or OHT(group-1), previous recurrent anterior uveitis(≥3 attacks) without glaucoma or OHT(group-2), and normal subjects with no ocular problems and IOP<21mmHg at screening, formed the control group(group-3). METHODS: Patients had one-off measurements. Group-1 patients who were on anti-hypertensives, were washed out for a 4-week period, prior to their study measurements. MAIN OUTCOME MEASURE: Tonographic outflow facility, aqueous flow rate and uveoscleral outflow. RESULTS: One hundred and one patients were screened between February 2014 and February 2017. Nine patients did not meet the inclusion criteria. Groups-1 and-3 each included 30 patients, and group-2 included 32 patients. The mean IOP was higher in the group-1 compared to the others(25±10.2(group-1) vs 16±2.7(group-2) vs 16±2.2mmHg(group-3), p