Factor VIII genotype characterization of haemophilia A affected patients with transient and permanent inhibitors: A comprehensive Argentine study of inhibitor risks | ORKG Ask

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F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

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F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis.

Gouw, S.C.
Berg, H.M. van den
Oldenburg, J.
Astermark, J.
Groot, P.G. de
Margaglione, M.
Thompson, A.R.
Heerde, W.L. van
Boekhorst, J.
Miller, C.H.
Cessie, S. le
Bom, J.G. Van Der

January 2012

This systematic review was designed to provide more precise effect estimates of inhibitor developmen...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia a

September 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...

F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

Gouw, Samantha C.
van den Berg, H. Marijke
Oldenburg, Johannes
Astermark, Jan
de Groot, Philip G.
Margaglione, Maurizio
Thompson, Arthur R.
van Heerde, Waander
Boekhorst, Jorien
Miller, Connie H.
le Cessie, Saskia
van der Bom, Johanna G.

January 2012

This systematic review was designed to provide more precise effect estimates of inhibitor developmen...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A.

January 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

September 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...

Genetic Characterization of the Factor VIII Gene in a Cohort of Colombian Patients with Severe Hemophilia A with Inhibitors

Samuel Sarmiento Doncel
Gina Alejandra Diaz Mosquera
Ronald Guillermo Pelaez
Javier Mauricio Cortes
Carol Agudelo Rico
Francisco Javier Meza Cadavid
Nelson Ramirez Plazas
Ivan Alfredo Perdomo Amar
Jorge Enrique Peña Siado
Fabian Andres Parrado Rey
Cesar Alberto Montaño
Alexys Maza Villadiego

May 2022

Hemophilia A is an X-linked bleeding disorder caused by mutations in the FVIII gene. Genetic factors...

Assessment of the F9 genotype-specific FIX inhibitor risks and characterization of 10 novel severe F9 defects in the first molecular series of Argentine patients with haemophilia B

Radic, Claudia Pamela
Rossetti, Liliana Carmen
Abelleyro, Miguel Martin
Candela, Miguel
Pérez Bianco, Raúl
de Tezanos Pinto, Miguel
Larripa, Irene Beatriz
Goodeve, Anne
de Brasi, Carlos Daniel

January 2013

In haemophilia B (HB) (factor IX [FIX] deficiency), F9 genotype largely determines clinical phenotyp...

Sevenfold risk for inhibitors in mild/moderate hemophilia A with factor VIII missense mutations in two distinct regions

Eckhardt, C.
Van Velzen, A.S.
Peters, M.
Streefkerk, N.
Astermark, J.
Oldenburg, J.
Peerlinck, K.
Hay, C.R.M.
Kamphuisen, P.-W.
Santagostino, E.
Van Der Bom, J.G.
Fijnvandraat, K.

July 2011

Introduction: Inhibitor development is a severe complication of mild/ moderate hemophilia A (MHA) an...

Factor VIII gene (F8) mutation and inhibitor development in non-severe hemophilia A

De Groot-Eckhardt, C. L.
Van Velzen, A. S.
Peters, Marloes
Peerlinck, K.
Oldenburg, J.
Santagostino, E.
Astermark, J.
Van Heerde, W. L.
Hermans, C.
Morfini, M.
Castaman, G.
Haya, S.
McRae, S.
Reitter-Pfoertner, S. E.
Kamphuisen, P. W.
Van der Bom, J. G.
Fijnvandraat, K. J.

July 2013

Background: The development of neutralizing antibodies (inhibitors) towards factor VIII is a major c...

CTLA4 p.Thr17Ala (c.49A>G) polymorphism associates with inhibitor development in argentine patients with severe hemophilia A

Marchione, Vanina Daniela
Radic, Claudia Pamela
Abelleyro, Miguel Martin
Primiani, L.
Neme, D.
Candela, M.
de Tezanos Pinto, M.
de Brasi, Carlos Daniel
Rossetti, Liliana Carmen

December 2016

El desarrollo de inhibidores de FVIII en hemofilia A (HA) es considerado un rasgo complejo, ya que i...

Reliable and cost-effective approach for diagnosis of heterozygous F8/F9 large deletions by quantitative real-time PCR

Abelleyro, Miguel Martin
Radic, Claudia Pamela
Tetzlaff, Guillermo Tomás
Marchione, Vanina Daniela
Fundia, Ariela Freya
Larripa, Irene Beatriz
Rossetti, Liliana Carmen
de Brasi, Carlos Daniel

March 2015

Haemophilia A (HA) (OMIM#306700) and haemophilia B (HB) (OMIM#306900) are X-linked disorders charact...

F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis.

Gouw, S.C.
Berg, H.M. van den
Oldenburg, J.
Astermark, J.
Groot, P.G. de
Margaglione, M.
Thompson, A.R.
Heerde, W.L. van
Boekhorst, J.
Miller, C.H.
Cessie, S. le
Bom, J.G. Van Der

January 2012

This systematic review was designed to provide more precise effect estimates of inhibitor developmen...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia a

September 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...

F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

Gouw, Samantha C.
van den Berg, H. Marijke
Oldenburg, Johannes
Astermark, Jan
de Groot, Philip G.
Margaglione, Maurizio
Thompson, Arthur R.
van Heerde, Waander
Boekhorst, Jorien
Miller, Connie H.
le Cessie, Saskia
van der Bom, Johanna G.

January 2012

This systematic review was designed to provide more precise effect estimates of inhibitor developmen...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A.

January 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...

Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

September 2013

Neutralizing antibodies (inhibitors) toward factor VIII form a severe complication in nonsevere hemo...