In this study, we explained in detail a targeted nano-photo-thermal therapy (NPTT) method to induce selective apoptosis in cancer cells. Folate-conjugated gold nanoparticles (F-AuNPs) were synthesized by tailoring the surface of AuNPs with folic acid to enhance the specificity of NPTT. KB cancer cells, as a folate receptor over-expressing cell line, and L929 normal cells with low level of folate receptors were incubated with the synthesized F-AuNPs and then irradiated with various laser intensities and exposure durations. Following various regimes of NPTT, we assessed the level of cell viability and the ratio of apoptosis/necrosis. No significant cytotoxicity was observed for both cell lines at concentrations up to 40�μM of F-AuNPs. More...
The use of nanoparticles has been investigated as a new cancer treatment. These can induce specific ...
A major challenge in designing cancer therapies is the induction of cancer cell apoptosis, although ...
Efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and t...
In this study, we explained in detail a targeted nano-photo-thermal therapy (NPTT) method to induce ...
Here, we report our research on the optimum design, in vitro tests and in vivo applications of folat...
Gold nanorods functionalised with transferrin were used for photothermally induced necrosis and apop...
Gold nanorods functionalised with transferrin were used for photothermally induced necrosis and apop...
The use of lasers has emerged to be highly promising for cancer therapy modalities, most commonly, t...
Background: Gold nanoparticles (AuNPs), owing to their elegant physicochemical properties, have rece...
The photothermal response of plasmonic nanomaterials can be exploited for a number of biomedical app...
Many tumor-targeted strategies have been used worldwide to limit the side effects and improve the ef...
Many tumor-targeted strategies have been used worldwide to limit the side effects and improve the ef...
Conventional cancer treatment methods suffer from many limitations such as non-specificity and low e...
Photothermal therapy (PTT) is a nanotechnology-assisted cancer hyperthermia approach in which the in...
Efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and t...
The use of nanoparticles has been investigated as a new cancer treatment. These can induce specific ...
A major challenge in designing cancer therapies is the induction of cancer cell apoptosis, although ...
Efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and t...
In this study, we explained in detail a targeted nano-photo-thermal therapy (NPTT) method to induce ...
Here, we report our research on the optimum design, in vitro tests and in vivo applications of folat...
Gold nanorods functionalised with transferrin were used for photothermally induced necrosis and apop...
Gold nanorods functionalised with transferrin were used for photothermally induced necrosis and apop...
The use of lasers has emerged to be highly promising for cancer therapy modalities, most commonly, t...
Background: Gold nanoparticles (AuNPs), owing to their elegant physicochemical properties, have rece...
The photothermal response of plasmonic nanomaterials can be exploited for a number of biomedical app...
Many tumor-targeted strategies have been used worldwide to limit the side effects and improve the ef...
Many tumor-targeted strategies have been used worldwide to limit the side effects and improve the ef...
Conventional cancer treatment methods suffer from many limitations such as non-specificity and low e...
Photothermal therapy (PTT) is a nanotechnology-assisted cancer hyperthermia approach in which the in...
Efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and t...
The use of nanoparticles has been investigated as a new cancer treatment. These can induce specific ...
A major challenge in designing cancer therapies is the induction of cancer cell apoptosis, although ...
Efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and t...