Mesoporous silica nanocarriers as accommodate drug molecule capsules were synthesized and capped by chitosan natural polymer. This nanocarrier acts as a pH-responsive shield to increase the solubility and improvement of anticancer properties of curcumin against U87MG glioblastoma cancer cell line. The encapsulation efficiency and drug-loading content were measured 88.1 ± 4.76 and 8.81 ± 0.47, respectively. The curcumin release from the CS-MCM-41 was slow and sustained at low pH (42.72 ± 2.29) compared to the environment pH (19.54 ± 1.36) in 96 h. The MTT evaluations showed that IC50 after 72 h treatment with free curcumin and curcumin-loaded CS-MCM-41 were 15.20 and 5.21 lg/mL (p<0.05). respectively. © 2017 Informa UK Limited, tradi...
Aims: Enhancement of anti-tumor activity of the chemotherapeutic agent CUR by redox-sensitive nanopa...
There is increasing interest in the use of natural compounds with beneficial pharmacological effects...
Curcumin, the active constituent of the rhizome Curcuma longa has been extensively studied as an ant...
Nanotechnology has many potential applications in cancer treatment. For example, nano-drug delivery ...
We designed and synthesized aminated mesoporous silica (MSN-NH2), and functionally grafted alginate ...
Purpose: Many natural agents have a high anticancer potential, and their combination may be advantag...
Curcumin is an active ingredient isolated from Curcuma longa. It has several pharmacological effects...
Mesoporous silica nanoparticles (MSN) with large surface areas and pore volumes show great potential...
Mesoporous silica nanoparticles (MSN) offer so many advantages as drug carrier, including large surf...
Breast cancer is the primary reason for cancer-related death in women worldwide and the development ...
Using of curcumin as anti cancer agent is restricted by its low solubility, therefore it has low bio...
nanoparticles for enhanced anti-colorectal cancer applications Panisa Udompornmongkol and Been-Huang...
In the present work, a simple method was used to develop composite curcumin-amine functionalized mes...
Curcumin, the yellow powder derived from the plant Curcuma Longa, exhibited numerous therapeutic ap...
Recently, the development of anti-cancer approaches using different physical or chemical pathways ha...
Aims: Enhancement of anti-tumor activity of the chemotherapeutic agent CUR by redox-sensitive nanopa...
There is increasing interest in the use of natural compounds with beneficial pharmacological effects...
Curcumin, the active constituent of the rhizome Curcuma longa has been extensively studied as an ant...
Nanotechnology has many potential applications in cancer treatment. For example, nano-drug delivery ...
We designed and synthesized aminated mesoporous silica (MSN-NH2), and functionally grafted alginate ...
Purpose: Many natural agents have a high anticancer potential, and their combination may be advantag...
Curcumin is an active ingredient isolated from Curcuma longa. It has several pharmacological effects...
Mesoporous silica nanoparticles (MSN) with large surface areas and pore volumes show great potential...
Mesoporous silica nanoparticles (MSN) offer so many advantages as drug carrier, including large surf...
Breast cancer is the primary reason for cancer-related death in women worldwide and the development ...
Using of curcumin as anti cancer agent is restricted by its low solubility, therefore it has low bio...
nanoparticles for enhanced anti-colorectal cancer applications Panisa Udompornmongkol and Been-Huang...
In the present work, a simple method was used to develop composite curcumin-amine functionalized mes...
Curcumin, the yellow powder derived from the plant Curcuma Longa, exhibited numerous therapeutic ap...
Recently, the development of anti-cancer approaches using different physical or chemical pathways ha...
Aims: Enhancement of anti-tumor activity of the chemotherapeutic agent CUR by redox-sensitive nanopa...
There is increasing interest in the use of natural compounds with beneficial pharmacological effects...
Curcumin, the active constituent of the rhizome Curcuma longa has been extensively studied as an ant...