Background: Toll-like receptor (TLR)-mediated inflammatory processes are supposed to be involved in pathophysiology of spontaneous abortion and preterm labor. Here, we investigated functional responses of human endometrial stromal cells (ESCs) and whole endometrial cells (WECs) to lipopolysaccharide (LPS) and lipoteichoic acid (LTA). Methods: Endometrial tissues were obtained from 15 cycling women who underwent laparoscopic tubal ligation. Modulation of TLR2, TLR4 and MyD88 expression and production of pro-inflammatory cytokines by WECs and ESCs in response to LPS and LTA were assessed. Results: WECs and ESCs expressed significant levels of TLR4 and MyD88 transcripts but, unlike WECs, ESCs failed to express TLR2 gene. Regardless of positive...
Background: Maternal–fetal tolerance plays a fundamental role in the maintenance of pregnancy. Howev...
Does activation of endometrial Toll-like receptor 3 (TLR 3) affect cell receptivity to trophoblast a...
International audienceThe female reproductive tract (FRT) is the main site of entry of sexually tran...
Background: Toll-like receptor (TLR)-mediated inflammatory processes are supposed to be involved in ...
Objectives: Vitamin D has potent immunoregulatory features and modulates innate and adaptive immune ...
yesThe aim of the study was to establish the association between expression of TLR1 (ligands - triac...
Endometriosis is an estrogen-dependent chronic inflammatory condition associated with variable degre...
Prostaglandins have a central role in many endocrine functions in mammals, including regulation of t...
Background: The human endometrium is an important site for contact between the host and pathogens as...
Bacteria often infect the endometrium of cattle to cause endometritis, uterine disease, and infertil...
. The present study tested the hypothesis that TLR4 on endometrial epithelial and stromal cells is e...
Inflammation of the uterus and oviduct is associated with reduced reproductive performance in humans...
<p>Stromal (A–D) and epithelial cells (E–H) isolated from the endometrium of Tlr4<sup>−/−</sup> mice...
First report of the role of TLR4 in innate immunity in the endometrium using TLR4 null mice
Background: Endometriosis is an estrogen-dependent, pro-inflammatory, pro-angiogenic condition that ...
Background: Maternal–fetal tolerance plays a fundamental role in the maintenance of pregnancy. Howev...
Does activation of endometrial Toll-like receptor 3 (TLR 3) affect cell receptivity to trophoblast a...
International audienceThe female reproductive tract (FRT) is the main site of entry of sexually tran...
Background: Toll-like receptor (TLR)-mediated inflammatory processes are supposed to be involved in ...
Objectives: Vitamin D has potent immunoregulatory features and modulates innate and adaptive immune ...
yesThe aim of the study was to establish the association between expression of TLR1 (ligands - triac...
Endometriosis is an estrogen-dependent chronic inflammatory condition associated with variable degre...
Prostaglandins have a central role in many endocrine functions in mammals, including regulation of t...
Background: The human endometrium is an important site for contact between the host and pathogens as...
Bacteria often infect the endometrium of cattle to cause endometritis, uterine disease, and infertil...
. The present study tested the hypothesis that TLR4 on endometrial epithelial and stromal cells is e...
Inflammation of the uterus and oviduct is associated with reduced reproductive performance in humans...
<p>Stromal (A–D) and epithelial cells (E–H) isolated from the endometrium of Tlr4<sup>−/−</sup> mice...
First report of the role of TLR4 in innate immunity in the endometrium using TLR4 null mice
Background: Endometriosis is an estrogen-dependent, pro-inflammatory, pro-angiogenic condition that ...
Background: Maternal–fetal tolerance plays a fundamental role in the maintenance of pregnancy. Howev...
Does activation of endometrial Toll-like receptor 3 (TLR 3) affect cell receptivity to trophoblast a...
International audienceThe female reproductive tract (FRT) is the main site of entry of sexually tran...