Leishmaniasis is a major infectious disease caused by protozoan parasites of the genus Leishmania. Despite of many efforts toward vaccine against Leishmania no effective vaccine has been approved yet. DNA vaccines can generate more powerful and broad immune responses than conventional vaccines. In order to increase immunity, the DNA vaccine has been supplemented with adjuvant. In this study a new nano-vaccine containing TSA recombinant plasmid and poly(methylmethacrylate) nanoparticles (act as adjuvant) was designed and its immunogenicity tested on BALB/c mouse. After three intramuscular injection of nano-vaccine (100 μg), the recombinant TSA protein (20 μg) was injected subcutaneously. Finally as a challenge animals were infected by Le...
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus Leishmania ...
Visceral leishmaniasis (VL) is a fatal disease when acute and untreated. The treatment against this ...
Background and Significance. The leishmaniases are a diverse group of diseases with four major clini...
Leishmaniasis is an important disease in humans. Leishmania homologue of receptor for Activated C Ki...
Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne d...
Background and Significance. The only immunizing intervention shown to be effective for preventing h...
Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne d...
International audienceThe leishmaniases are protozoal diseases that severely affect large population...
We used TSA as a principal antigen of Leishmania major with adjuvants. The aim of this research was ...
Background: Leishmaniasis is caused by parasitic protozoa of the genus Leishmania which is an obliga...
Vaccine delivery using microneedles (MNs) represents a safe, easily disposable and painless alternat...
International audienceLeishmaniasis is the 3rd most challenging vector-borne disease after malaria a...
BACKGROUND: Visceral leishmaniasis (VL) caused by an intracellular protozoan parasite Leishmania, is...
AbstractThe VR1012NH36 DNA vaccine was immunoprophylactic and immunotherapeutic against mice viscera...
Leishmaniasis, a spectrum of diseases caused by various forms of Leishmania has become a major healt...
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus Leishmania ...
Visceral leishmaniasis (VL) is a fatal disease when acute and untreated. The treatment against this ...
Background and Significance. The leishmaniases are a diverse group of diseases with four major clini...
Leishmaniasis is an important disease in humans. Leishmania homologue of receptor for Activated C Ki...
Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne d...
Background and Significance. The only immunizing intervention shown to be effective for preventing h...
Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne d...
International audienceThe leishmaniases are protozoal diseases that severely affect large population...
We used TSA as a principal antigen of Leishmania major with adjuvants. The aim of this research was ...
Background: Leishmaniasis is caused by parasitic protozoa of the genus Leishmania which is an obliga...
Vaccine delivery using microneedles (MNs) represents a safe, easily disposable and painless alternat...
International audienceLeishmaniasis is the 3rd most challenging vector-borne disease after malaria a...
BACKGROUND: Visceral leishmaniasis (VL) caused by an intracellular protozoan parasite Leishmania, is...
AbstractThe VR1012NH36 DNA vaccine was immunoprophylactic and immunotherapeutic against mice viscera...
Leishmaniasis, a spectrum of diseases caused by various forms of Leishmania has become a major healt...
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus Leishmania ...
Visceral leishmaniasis (VL) is a fatal disease when acute and untreated. The treatment against this ...
Background and Significance. The leishmaniases are a diverse group of diseases with four major clini...