This account highlights the most relevant transformations of cycloalkane-fused oxiranes and aziridines developed during the past decade with the intention to provide an overview of the ring-opening synthetic techniques towards different functionalized cycloalkanes in racemic or enantiomerically pure form. It focuses also on the regioselectivity/regiocontrol and enantioselectivity of ring-opening methodologies including unsymmetrical cycloalkane-fused oxiranes and aziridines. (C) 2017 Elsevier Ltd. All rights reserved
Aziridines are three-membered cyclic heterocycles that contain a nitrogen atom in the ring. The larg...
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition re...
Most nucleophilic aziridine ring opening reactions suffer from poor regio- and stereoselectivity. A ...
The current minireview highlights the most relevant methodologies for the creation of fluorinated s...
Abstract: The synthesis of aziridine-2-carboxylic acid derivatives of high enantiopurity is describe...
The regiochemical outcome of the ring opening of aziridines bearing a polar remote functionality was...
Aziridines, the nitrogenous analogues of epoxides, are useful building blocks for the synthesis of v...
The regiochemical outcome of the ring opening of the activated and unactivated title aziridines was ...
Some recent advances in the field of stereoselective synthesis of aziridines focusing on new methodo...
Chapter 1 Overview of enantioselective desymmetrisations of prochiral and mesocompounds A molecule i...
The common theme throughout this research was the search for new tools and routes to effect useful c...
The current minireview highlights the most relevant methodologies for the creation of fluorinated sc...
The ring-opening of aziridines by pendant sulfamates is a viable strategy for the rapid preparation ...
Aziridinium ions are valuable reactive intermediates in organic synthesis. Regioselective and stereo...
(S)-3-Amino-2-(1-hydroxy-2,2-dimethylprop-1-yl)-quinazolin-4(3H)-one (Q*NH2) was prepared from (L)-t...
Aziridines are three-membered cyclic heterocycles that contain a nitrogen atom in the ring. The larg...
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition re...
Most nucleophilic aziridine ring opening reactions suffer from poor regio- and stereoselectivity. A ...
The current minireview highlights the most relevant methodologies for the creation of fluorinated s...
Abstract: The synthesis of aziridine-2-carboxylic acid derivatives of high enantiopurity is describe...
The regiochemical outcome of the ring opening of aziridines bearing a polar remote functionality was...
Aziridines, the nitrogenous analogues of epoxides, are useful building blocks for the synthesis of v...
The regiochemical outcome of the ring opening of the activated and unactivated title aziridines was ...
Some recent advances in the field of stereoselective synthesis of aziridines focusing on new methodo...
Chapter 1 Overview of enantioselective desymmetrisations of prochiral and mesocompounds A molecule i...
The common theme throughout this research was the search for new tools and routes to effect useful c...
The current minireview highlights the most relevant methodologies for the creation of fluorinated sc...
The ring-opening of aziridines by pendant sulfamates is a viable strategy for the rapid preparation ...
Aziridinium ions are valuable reactive intermediates in organic synthesis. Regioselective and stereo...
(S)-3-Amino-2-(1-hydroxy-2,2-dimethylprop-1-yl)-quinazolin-4(3H)-one (Q*NH2) was prepared from (L)-t...
Aziridines are three-membered cyclic heterocycles that contain a nitrogen atom in the ring. The larg...
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition re...
Most nucleophilic aziridine ring opening reactions suffer from poor regio- and stereoselectivity. A ...