Chromatin is a dynamic complex that controls access to genetic information by undergoing structural reconfigurations. Understanding this dynamic can provide insights into the biological implications of chromatin organisation. We have undertaken a detailed catalogue of the human core histone genes and contributed to their annotations. Based on the reproducible research concept, we produced this catalogue with a system that is capable to generate new up to date manuscripts as a model for similar projects which can be continually improved along with genome annotations. As proof of concept, we used the same project to produce a catalogue of the current mouse histone genes. Quantitative fluorescence microscopy has been used extensively to ...
Eukaryotic cells contain long DNA molecules which provide all the information for proper functioning...
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local D...
AbstractEukaryotic genomes, which comprise as many as 3 billion DNA bases, are packaged into a highe...
Eukaryotic DNA is packaged into chromatin to fit in the limited dimensions of the nucleus. The basic...
132 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.Interest in chromatin biology...
AbstractChromatin is the macromolecular nucleoprotein complex that governs the organization of genet...
DNA is a key component of almost all cells, but it is not the sole determinant of the cellular funct...
Dissertation (Ph.D.)--University of Kansas, Chemistry, 2004.Chromatin, the DNA-protein complex is be...
The human body consists of billions of cells. These cells are not all the same, but they differ in s...
In eukaryotic cells, the genome is packaged into chromatin and exists in different states, ranging f...
Nucleosomes are essential for proper chromatin organization and the maintenance of genome integrity....
Histone-based chromatin organization paved the way for eukaryotic genome complexity. Because oftheir...
The work presented in this thesis aims at unravelling human chromatin composition by quantitative p...
Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable ...
In eukaryotes, nucleosomes form a barrier to DNA templated reactions and must be dynamically disrupt...
Eukaryotic cells contain long DNA molecules which provide all the information for proper functioning...
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local D...
AbstractEukaryotic genomes, which comprise as many as 3 billion DNA bases, are packaged into a highe...
Eukaryotic DNA is packaged into chromatin to fit in the limited dimensions of the nucleus. The basic...
132 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.Interest in chromatin biology...
AbstractChromatin is the macromolecular nucleoprotein complex that governs the organization of genet...
DNA is a key component of almost all cells, but it is not the sole determinant of the cellular funct...
Dissertation (Ph.D.)--University of Kansas, Chemistry, 2004.Chromatin, the DNA-protein complex is be...
The human body consists of billions of cells. These cells are not all the same, but they differ in s...
In eukaryotic cells, the genome is packaged into chromatin and exists in different states, ranging f...
Nucleosomes are essential for proper chromatin organization and the maintenance of genome integrity....
Histone-based chromatin organization paved the way for eukaryotic genome complexity. Because oftheir...
The work presented in this thesis aims at unravelling human chromatin composition by quantitative p...
Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable ...
In eukaryotes, nucleosomes form a barrier to DNA templated reactions and must be dynamically disrupt...
Eukaryotic cells contain long DNA molecules which provide all the information for proper functioning...
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local D...
AbstractEukaryotic genomes, which comprise as many as 3 billion DNA bases, are packaged into a highe...