7α-Dehydrogenation of taurocholic acid and glycocholic acid by Escherichia coli (E. coli) was examined in aerobic and anaerobic culture conditions. Bile acids in the culture medium of E. coli were extracted, separated into free, glycine-conjugate and taurine-conjugate fractions by piperidinohydroxypropyl dextran gel column chromatography, hydrolyzed in alkali and analyzed by gas-liquid chromatography. Both conjugated cholic acids were dehydrogenated to the corresponding 3α,12α-dihydroxy-7-oxo-5β-cholan oic acid without deconjugation and no deconjugation of both conjugated cholic acid was detected in aerobic cultures. But there was little transformation in anaerobic cultures. These data suggest that conjugated cholic acids are taken up by E....
Bile acids are important signaling molecules that regulate cholesterol, glucose, and energy homoeost...
Isoprenoic compounds play a major part in the global carbon cycle. Biosynthesis and mineralization b...
Eleven strains of lactobacilli were screened for their bile salt deconjugation ability, bile salt hy...
The oxidation/reduction reactions of bile acids by Escherichia coli (E. coli) K-12 were examined in ...
The effects of Bacteroides sp. strain T-40 isolated from human feces on the biotransformation of bil...
Bile acids are C24 steroids that are derived in the liver from cholesterol and secreted into the int...
<p>Flow diagram showing the metabolism and fate of bile acids. In the liver (orange arrows), cholest...
Bile acids are one group of steroids that can be metabolically transformed by human gut anaerobes. O...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids are surface-active steroid compounds with toxic effects for bacteria. Recently, the isola...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids are surface-active steroid compounds with toxic effects for bacteria. Recently, the isola...
Bile acids (BAs) are small molecules synthesized by the host and chemically modified by the microorg...
and deoxycholyl-2,4-3H-glycine-1-14C were synthesized and administered orally to 10 healthy subjects...
Bile acids are important signaling molecules that regulate cholesterol, glucose, and energy homoeost...
Isoprenoic compounds play a major part in the global carbon cycle. Biosynthesis and mineralization b...
Eleven strains of lactobacilli were screened for their bile salt deconjugation ability, bile salt hy...
The oxidation/reduction reactions of bile acids by Escherichia coli (E. coli) K-12 were examined in ...
The effects of Bacteroides sp. strain T-40 isolated from human feces on the biotransformation of bil...
Bile acids are C24 steroids that are derived in the liver from cholesterol and secreted into the int...
<p>Flow diagram showing the metabolism and fate of bile acids. In the liver (orange arrows), cholest...
Bile acids are one group of steroids that can be metabolically transformed by human gut anaerobes. O...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids are surface-active steroid compounds with toxic effects for bacteria. Recently, the isola...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids, the products of concerted host and gut bacterial metabolism, have important signaling fu...
Bile acids are surface-active steroid compounds with toxic effects for bacteria. Recently, the isola...
Bile acids (BAs) are small molecules synthesized by the host and chemically modified by the microorg...
and deoxycholyl-2,4-3H-glycine-1-14C were synthesized and administered orally to 10 healthy subjects...
Bile acids are important signaling molecules that regulate cholesterol, glucose, and energy homoeost...
Isoprenoic compounds play a major part in the global carbon cycle. Biosynthesis and mineralization b...
Eleven strains of lactobacilli were screened for their bile salt deconjugation ability, bile salt hy...