Industry 4.0 is a word that identifies innovative technologies, processes and products, typical of a Fourth Industrial Revolution characterised by a massive and pervasive use of interdependent digital technologies and the rise of cyber-physical spaces or smart factories. European Member States are committed to adapting their innovation systems in order to be able to benefit from Industry 4.0 and the European Commission is also facing the challenge of putting less advanced regions in a position to do so. However, little is known about the drivers of the capacity to compete in the domain of Industry 4.0 by integrating different enabling technologies at the regional level. On the basis of data on regional participation in the 7th European Fram...