Data from: Development of MHC-linked microsatellite markers in the domestic cat and their use to evaluate MHC diversity in domestic cats, cheetahs and Gir lions.
- Morris, Katrina M.
- Kirby, Katherine
- Beatty, Julia A.
- Barrs, Vanessa R.
- Cattley, Sonia
- David, Victor
- O'Brien, Stephen J.
- Menotti-Raymond, Marilyn
- Belov, Katherine
DOIAbstract
Diversity within the major histocompatibility complex (MHC) reflects the immunological fitness of a population. MHC-linked microsatellite markers provide a simple and inexpensive method for studying MHC diversity in large scale studies. We have developed six MHC-linked microsatellite markers in the domestic cat and used these, in conjunction with five neutral microsatellites, to assess MHC diversity in domestic mixed breed (n = 129) and purebred Burmese (n = 61) cat populations in Australia. The MHC of outbred Australian cats is polymorphic (average allelic richness = 8.52) while the Burmese population has much significantly lower MHC diversity (average allelic richness = 6.81; P<0.01). The MHC-linked microsatellites along with MHC cloning ...
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