International audienceA rapid transient rise in the free cytosolic Ca2+ concentration is one of the earliest events in smooth muscle cell activation and is involved in the opening of several classes of Ca2(+)-sensitive ion channels such as K+ channels and Cl- channels. In portal vein smooth muscle cells, in addition to the Ca(2+)-dependent Cl-current, single-channel activities were recorded in response to external application of 10 mM caffeine, in the absence of EGTA in the pipette solution. The conductance of this novel type of channel was around 200 pS for membrane potentials ranging between -100 to +60 mV. The single-channel activities were also induced by external application of noradrenaline (10(-5) M) or acetylcholine (10(-5) M), by C...
1. The Ca2+-sensitive fluorescent indicator rhod-2 was used to measure mitochondrial [Ca2+] ([Ca2+]m...
Voltage-dependent inward currents responsible for the depolarizing phase of action potentials were c...
1. The action of Ca2+ channel modulators has been examined on the intracellular Ca2+ signal in the l...
International audienceMembrane currents of isolated smooth muscle cells from rat portal vein were st...
The effects of caffeine on cytoplasmic [Ca2+] ([Ca2+]i) and plasma membrane currents were studied in...
Activation of ryanodine receptors on the sarcoplasmic reticulum of single smooth muscle cells from t...
The objectives of this study were as follows: (1) to establish a technique to determine (Ca$\sp{2+}\...
Vascular smooth muscle cells require a very precise regulation of intracellular calcium concentratio...
International audienceThe effects of noradrenaline (NA) were studied on vascular smooth muscle cells...
Transsarcolemmal influx and release from the sarcoplasmic reticulum (SR) through specific Ca2 '...
.Objective: To investigate the effects of stimulating calcium induced Ca release with low concentrat...
Changes in potential and mechanical activity were measured with the sucrose-gap method and changes i...
AbstractThe efflux of 45Ca2+ from preloaded intracellular stores of saponin-permeabilised human uter...
The inhibitory effect of caffeine on inward Ca?? current (Ica) was investigated in isolated single s...
The effect of the Cl− channel blockers niflumic acid (NFA), 5-nitro-2-(3-phenylpropylamino)-benzoic ...
1. The Ca2+-sensitive fluorescent indicator rhod-2 was used to measure mitochondrial [Ca2+] ([Ca2+]m...
Voltage-dependent inward currents responsible for the depolarizing phase of action potentials were c...
1. The action of Ca2+ channel modulators has been examined on the intracellular Ca2+ signal in the l...
International audienceMembrane currents of isolated smooth muscle cells from rat portal vein were st...
The effects of caffeine on cytoplasmic [Ca2+] ([Ca2+]i) and plasma membrane currents were studied in...
Activation of ryanodine receptors on the sarcoplasmic reticulum of single smooth muscle cells from t...
The objectives of this study were as follows: (1) to establish a technique to determine (Ca$\sp{2+}\...
Vascular smooth muscle cells require a very precise regulation of intracellular calcium concentratio...
International audienceThe effects of noradrenaline (NA) were studied on vascular smooth muscle cells...
Transsarcolemmal influx and release from the sarcoplasmic reticulum (SR) through specific Ca2 '...
.Objective: To investigate the effects of stimulating calcium induced Ca release with low concentrat...
Changes in potential and mechanical activity were measured with the sucrose-gap method and changes i...
AbstractThe efflux of 45Ca2+ from preloaded intracellular stores of saponin-permeabilised human uter...
The inhibitory effect of caffeine on inward Ca?? current (Ica) was investigated in isolated single s...
The effect of the Cl− channel blockers niflumic acid (NFA), 5-nitro-2-(3-phenylpropylamino)-benzoic ...
1. The Ca2+-sensitive fluorescent indicator rhod-2 was used to measure mitochondrial [Ca2+] ([Ca2+]m...
Voltage-dependent inward currents responsible for the depolarizing phase of action potentials were c...
1. The action of Ca2+ channel modulators has been examined on the intracellular Ca2+ signal in the l...