Background: Angiogenesis is an important step in the metastatic cascade of tumors. Results: MMP-13 itself as well as VEGF-A secretion from fibroblasts promotes angiogenesis. Indeed, MMP-13 is well correlated with blood vessel density in human cancer tissues. Conclusion: MMP-13 can be a marker for prediction of malignant behaviors and a therapeutic target in cancer. Significance: This work provides new insights regarding the role of MMP-13 in tumor angiogenesis
Membrane type 1 metalloprotease (MT1-MMP) is a transmembrane metalloprotease that plays a major role...
Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that ...
Inhibition of matrix-metalloproteinases (MMPs) by tissue inhibitors of metalloproteinases (TIMPs) ha...
AbstractA number of extensive reviews are available discussing the roles of MMPs in various aspects ...
Matrix metalloproteinase-13 (MMP-13) is a member of the Matrix metalloproteinases (MMPs) family of e...
Colorectal cancer is the third most common cancer in the world, and it is the fourth most common cau...
Membrane-type 1 matrix metalloproteinase (MT1-MMP) and vascular endothelial growth factor ( VEGF) ar...
The matrix metalloproteinases (MMPs) constitute a multigene family of over 23 secreted and cell-surf...
Introduction: Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) a...
peer reviewedAmong matrix metalloproteinases (MMP), MMP-19 displays unique structural features and t...
Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that process growth factors, gr...
Background: An important step of tumor progression in which Matrix metalloproteinase have been impli...
Matrix metalloproteinases (MMPs) are required for tissue remodelling processes, including angiogene...
Tumor invasion and metastasis of malignant melanoma have been shown to require proteolytic degradati...
Extracellular matrix degradation by matrix metalloproteinases (MMPs) plays a pivotal role in cancer ...
Membrane type 1 metalloprotease (MT1-MMP) is a transmembrane metalloprotease that plays a major role...
Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that ...
Inhibition of matrix-metalloproteinases (MMPs) by tissue inhibitors of metalloproteinases (TIMPs) ha...
AbstractA number of extensive reviews are available discussing the roles of MMPs in various aspects ...
Matrix metalloproteinase-13 (MMP-13) is a member of the Matrix metalloproteinases (MMPs) family of e...
Colorectal cancer is the third most common cancer in the world, and it is the fourth most common cau...
Membrane-type 1 matrix metalloproteinase (MT1-MMP) and vascular endothelial growth factor ( VEGF) ar...
The matrix metalloproteinases (MMPs) constitute a multigene family of over 23 secreted and cell-surf...
Introduction: Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) a...
peer reviewedAmong matrix metalloproteinases (MMP), MMP-19 displays unique structural features and t...
Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that process growth factors, gr...
Background: An important step of tumor progression in which Matrix metalloproteinase have been impli...
Matrix metalloproteinases (MMPs) are required for tissue remodelling processes, including angiogene...
Tumor invasion and metastasis of malignant melanoma have been shown to require proteolytic degradati...
Extracellular matrix degradation by matrix metalloproteinases (MMPs) plays a pivotal role in cancer ...
Membrane type 1 metalloprotease (MT1-MMP) is a transmembrane metalloprotease that plays a major role...
Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that ...
Inhibition of matrix-metalloproteinases (MMPs) by tissue inhibitors of metalloproteinases (TIMPs) ha...