Analysis of Ventricular Repolarization Parameters

This bachelor’s thesis deals with the analysis of ventricular repolarization parameters on experimental ECG records. In the beginning of the theoretical part there are included information about heart electrophysiology, fundamental principle of ECG and cellular basis of the T-wave formation. Next chapter is focused on methods used for the analysis of ventricular repolarization, especially spatial parameters including principal component analysis (PCA). Then, in the thesis, there is described the database of experimental ECG signals created from isolated rabbit hearts. In the practical part of this bachelor’s thesis, there are implemented spatial parameters on experimental ECG records. Implementation of algorithms is performed after initial data preparation. Then, there is performed analysis of relation between spatial and hemodynamic parameters and the relation is evaluated by statistical analysis