Synthesis and characterization of chiral gold (I) phosphine complexes with new dithiophosphorus ligands

The novel chiral-centered amidodithiophosphonates [Fe(5-C 5H5)(5-C5H4P(= S)(SH)(NHR))] were synthesized by the reaction of [FcP(= S)(-S)]2 and chiral amines such as (R)-(+)-1-phenylethyl-amine, (S)-(-)-1-phenylethyl-amine, (R)-(+)-1- phenylpropyl-amine, (S)-(+)-3-methyl-2-butyl-amine, (S)-(+)-1-aminoindane, (-)-cis-myrtanylamine, and (1S,2S)-(+)-2-benzyloxycyclohexyl-amine in toluene. The reaction of chiral-centered amidoferrocenyldithiophosphonates and [(PPh 3)AuCl] gave rise to gold (I) complexes in CHCl3 or the CHCl 3-toluene mixtures. The ligands 1-7 and the complexes 1a, 3a, and 4a were characterized by elemental analyses, infrared (IR), nuclear magnetic resonance (NMR; 1H-, 31P-, 13C-) spectroscopy, as well as mass spectrometry (MS) measurements. Although amidodithiophosphonates are potential tridentate ligands, they are coordinated to gold only by one sulfur atom. The investigated chiral gold (I) complexes including two different phosphorus ligands are air stable. © 2011 Taylor & Francis Group, LLC