Relationship between subfoveal choroidal thickness, ocular pulse amplitude, and intraocular pressure in healthy subjects

Purpose: To investigate the correlation between subfoveal choroidal thickness (SFCT), ocular pulse amplitude (OPA), and intraocular pressure (IOP) in healthy individuals. Methods: In total, 106 eyes of 106 healthy adult participants were included in this cross-sectional study. Spectral-domain optical coherence tomography was used to measure the SFCT. OPA and IOP were measured with the Pascal dynamic contour tonometer. The Pearson correlation test was performed to examine the relationship between SFCT, OPA, and IOP. Results: When age, sex, and body mass index (BMI) were controlled separately, a weak correlation occurred between SFCT and OPA (age controlled, r=0.20; sex controlled, r=0.19; BMI controlled, r=0.13). SFCT and OPA were fairly correlated in older age (r=0.33, P=0.02) and low BMI (r=0.33, P=0.02). SFCT and IOP were not correlated statistically significantly (r=0.05, P=0.59). Conclusion: There is a weak correlation between SFCT and OPA in healthy individuals when age is controlled. The association becomes stronger in participants with low BMI. There is no relation between SFCT and IOP. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved