randomized controlled trial

Background. The aim of this study was to compare spinal anesthesia effects of low-dose hyperbaric levobupivacaine and low-dose hyperbaric bupivacaine for transurethral procedures.Methods. In this double-blind, randomized, controlled study, a total of 60 patients who were ASA I-III were randomized into two groups. Group B received 7.5 mg hyperbaric bupivacaine plus 25 mu g fentanyl, and Group L received 7.5 mg hyperbaric levobupivacaine plus 25 mu g fentanyl intrathecally. The onset time to T10 dermatome, times to maximum sensory and motor block levels, time to two-segment regression of sensory block, time to Bromage score zero, time to full recovery of sensory block, and hemodynamic values, as well as adverse effects, were recorded. The primary outcome was the time to complete regression of motor block.Results. The onset time of block to T10, time to maximum sensory block, and time to two-segment regression were similar in both groups. The time to maximum motor block was shorter in Group B (7 +/- 3 min) than in Group L (12 +/- 5 min), (P<0.001). The time to a Bromage score of zero (recovery of motor block) was shorter in Group L (105 +/- 19 min) than in Group B (113 +/- 7 min), (P=0.04). The time to full recovery of sensory block was shorter in Group B (127 14 min) than in Group L (157 34 min), (P