High inhaled oxygen concentration quadruples exhaled CO in healthy volunteers monitored by a highly sensitive laser spectrometer

Brenckmann, Vivien
Ventrillard, Irène
Romanini, Daniele
Jaulin, Kévin
Calabrese, Pascale
Briot, Raphael

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Publication date

August 2019

DOI

10.1038/s41598-019-48789-8

Publisher

Springer Science and Business Media LLC

Abstract

International audienceCarbon monoxide (CO) monitoring in human breath is the focus of many investigations as CO could possibly be used as a marker of various diseases. Detecting CO in human breath remains a challenge because low concentrations (<ppm) must be selectively detected and short response time resolution is needed to detect the end expiratory values reflecting actual alveolar concentrations. A laser spectroscopy based instrument was developed (ProCeas) that fulfils these requirements. The aim of this study was to validate the use of a ProCeas for human breath analysis in order to measure the changes of endogenous exhaled CO (eCO) induced by different inspired fractions of oxygen (FiO2) ranging between 21% and 100%. This study was p...

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High inhaled oxygen concentration quadruples exhaled CO in healthy volunteers monitored by a highly sensitive laser spectrometer

Abstract

Extracted data

High inhaled oxygen concentration quadruples exhaled CO in healthy volunteers monitored by a highly sensitive laser spectrometer

Abstract

Extracted data

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