This thesis investigates a part of the material culture of higher education through an object biographical case study of Félix Thibert’s moulages. The object biography operates with a diachronic perspective that offers an object-centered historiography of university collections, revealing that the need for collecting and imaging in science consistently remains, even though the role and significance of pathological moulages in research and education have changed over time. The moulages are epistemic things as described by Hans-Jörg Rheinberger. They embody what we do not yet know and they become marginalized when no one expects them to generate new discoveries. Their ontology and function are dependent on the dominating epistemic culture. Jo...