Functional diffusion magnetic resonance imaging

Functional diffusion magnetic resonance imaging (fDMRI) is a noninvasive technique that allows elucidating physiological and anatomical changes at a microscopic scale by detection of water molecular displacements in tissue structures. These displacements likely reflect microstructural changes associated with neuronal or glial cells activation. In this chapter, we will describe the physical and biological concepts of fDMRI and how images of brain activation can be acquired in a preclinical setup.This work was supported by grant SAF2014-53739-R. RMRO held a contract form the Programme Erasmus + and IG held a predoctoral contract from Ministerio de Economía, Indrustria y Competitividad (MINECO) of Spain.Peer reviewe