Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.
- Riesterer, O.
- Ciernik, I.F.
- Stahel, R.A.
- Xyrafas, A.
- Aebersold, D.M.
- Plasswilm, L.
- Mahmut Ozsahin, E.
- Zwahlen, D.R.
- Nackaerts, K.
- Zimmermann, F.
- Sabrina Stark, L.
- Weder, W.
- Krayenbuehl, J.
DOIAbstract
Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field
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