Grenz S, Baumann PT, Rückert C, et al. Exploiting Hydrogenophaga pseudoflava for aerobic syngas-based production of chemicals. Metabolic engineering. 2019;55:220-230.Gasification is a suitable technology to generate energy-rich synthesis gas (syngas) from biomass or waste streams, which can be utilized in bacterial fermentation processes for the production of chemicals and fuels. Established microbial processes currently rely on acetogenic bacteria which perform an energetically inefficient anaerobic CO oxidation and acetogenesis potentially hampering the biosynthesis of complex and ATP-intensive products. Since aerobic oxidation of CO is energetically more favorable, we exploit in this study the Gram-negative beta-proteobacterium Hydrogeno...