International audienceMost landscape evolution models adopt the paradigm of constant and uniform uplift. It results that the role of fault activity and earthquakes on landscape building is understood under simplistic boundary conditions. Here, we develop a numerical model to investigate river profile development subjected to fault displacement by earthquakes and erosion. The model generates earthquakes, including mainshocks and aftershocks, that respect the classical scaling laws observed for earthquakes. The distribution of seismic and aseismic slip can be partitioned following a spatial distribution of mainshocks along the fault plane. Slope patches, such as knickpoints, induced by fault slip are then migrated at a constant rate upstream ...