Finite element analysis of mechanical behavior, permeability of irregular porous scaffolds and lattice-based porous scaffolds

In view of the low elastic modulus of the porous structure, it has attracted extensive attention in the field of artificial tissue implants for bone tissue engineering, and it has become important to find a porous structure suitable for human bone tissue. In this study, we constructed three type regular porous structure (cube, diamond, rhombohedral dodecahedron) and an irregular porous structure based on Voronoi tessellation. Firstly, the structural characteristics of porous structures were studied. After permeation simulation and compression simulation, we found that the structural characteristics (porosity, pore size, specific surface area) of four porous structures have a strong positive correlation with permeability. With the increase of porosity, the effective elastic modulus of the four porous structures decreases gradually. When the porosity is 80%, the effective elastic modulus and permeability of the four porous structures can basically meet the requirements of human bone implants. Irregular porous scaffolds exhibit relatively limited anisotropy in terms of mechanical properties and permeability. In view of the similarity between the structure and the human bone, the irregular porous structure exhibits superior development and application potential compared to the regular porous structure